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Article

The impact of CYP19A1 variants and haplotypes on breast cancer risk, clinicopathological features and prognosis.

Molecular genetics & genomic medicine - 1 Jul 2021

Alwan Ahmad Mohammed, Afzaljavan Fahimeh, Tavakol Afshari Jalil, Homaei Shandiz Fatemeh, Barati Bagherabad Matineh, Vahednia Elham, Kheradmand Nahid, Pasdar Alireza

Abstract excerpt

BACKGROUND: Different genetic variants in hormone-regulating pathways have been identified to influence the risk of breast cancer. This study aimed to evaluate the association of CYP19A1 rs10046 and rs700519 polymorphisms with the risk, clinicopathological factors and prognosis of breast cancer. METHODS: In a case-control study, rs10046 and rs700519 polymorphisms were genotyped using ARMS-PCR and high-resolution...

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Identifiers

PMID: 34014013
DOI: 10.1002/mgg3.1705
PMCID: PMC8372086

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