Article
Androgen receptor genotypes predict response to endocrine treatment in breast cancer patients.
British journal of cancer - 22 Nov 2011
Lundin K B, Henningson M, Hietala M, Ingvar C, Rose C, Jernström H
Abstract excerpt
BACKGROUND: The androgen receptor (AR) is frequently expressed in breast cancers. The AR genotype may affect disease-free survival and response to endocrine therapy. METHODS: In all, 634 women undergoing breast cancer surgery between 2002 and 2008 were followed until 30 June 2010. Six haplotype-tagging single-nucleotide polymorphisms in the AR, and the resulting AR diplotypes, were examined in relation to breast...
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