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Article

Psychosis and relapse in bipolar disorder are related to GRM3, DAOA, and GRIN2B genotype.

African journal of psychiatry - 1 Sept 2010

Dalvie S, Horn N, Nossek C, van der Merwe L, Stein D J, Ramesar R

Abstract excerpt

OBJECTIVE: Dysfunction in glutamate signalling is thought to play a role in the pathophysiology of bipolar disorder (BD). There is evidence of associations between single nucleotide polymorphisms (SNPs) in GRM3, GRIN2B, and DAOA genes and the diagnosis of BD. In this pilot study, we investigated the frequency of SNP variants in these 3 genes within South African population groups, and assessed interactions...

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Source

Identifiers

PMID: 20957330
DOI: 10.4314/ajpsy.v13i4.61880

Genes

DAOA
GRM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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