Article
Genome-wide association study in bipolar patients stratified by co-morbidity.
PloS one - 1 Jan 2011
Kerner Berit, Lambert Christophe G, Muthén Bengt O
Abstract excerpt
BACKGROUND: Bipolar disorder is a severe psychiatric disorder with high heritability. Co-morbid conditions are common and might define latent subgroups of patients that are more homogeneous with respect to genetic risk factors. METHODOLOGY: In the Caucasian GAIN bipolar disorder sample of 1000 cases and 1034 controls, we tested the association of single nucleotide polymorphisms with patient subgroups defined by...
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