Article
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE).
Schizophrenia research - 1 Feb 2009
Djurovic S, Kähler A K, Kulle B, Jönsson E G, Agartz I, Le Hellard S, Hall H, Jakobsen K D, Hansen T, Melle I, Werge T, Steen V M, Andreassen O A
Abstract excerpt
There is considerable evidence of altered glutamatergic signalling in schizophrenia and a polymorphic variant of the GRIK3 glutamate receptor gene on 1p34-33 has previously been associated to this psychotic disorder. We therefore conducted a systematic association study with 30 HapMap-selected tagging SNPs across GRIK3 in three independent samples of Scandinavian origin from the Scandinavian Collaboration of...
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