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Article

Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.

Archives of general psychiatry - 1 Apr 2006

Williams Nigel M, Green Elaine K, Macgregor Stuart, Dwyer Sarah, Norton Nadine, Williams Hywel, Raybould Rachel, Grozeva Detelina, Hamshere Marian, Zammit Stanley, Jones Lisa, Cardno Alastair, Kirov George, Jones Ian, O'Donovan Michael C, Owen Michael J, Craddock Nick

Abstract excerpt

CONTEXT: Variation at the DAOA/G30 locus has been described to be associated with both schizophrenia and bipolar disorder, but there is little consistency between studies of the tested polymorphisms or variants showing association. OBJECTIVES: To obtain a stringent replication of association in large samples of both disorders using consistent clinical and laboratory methods, and to test the hypothesis that...

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Source

Identifiers

PMID: 16585465
DOI: 10.1001/archpsyc.63.4.366

Genes

DAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.PMID 16585465Read ↗

The DAOA/G30 locus and affective disorders: haplotype based association study in a polydiagnostic approach.Semantic proximity Read ↗

Association of DAO and G72(DAOA)/G30 genes with bipolar affective disorder.Semantic proximity Read ↗

D-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia.Semantic proximity Read ↗

Genome-wide association study identifies 30 Loci Associated with Bipolar DisorderSemantic proximity Read ↗

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes.Semantic proximity Read ↗

Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample.Semantic proximity Read ↗

Association between DAOA gene polymorphisms and the risk of schizophrenia, bipolar disorder and depressive disorder.Semantic proximity Read ↗

DAOA variants on diagnosis and response to treatment in patients with major depressive disorder and bipolar disorder.Semantic proximity Read ↗

Genetics of affective (mood) disorders.Semantic proximity Read ↗

Allelic association of G72/G30 with schizophrenia and bipolar disorder: a comprehensive meta-analysis.Semantic proximity Read ↗

Psychosis and relapse in bipolar disorder are related to GRM3, DAOA, and GRIN2B genotype.Semantic proximity Read ↗

An overview of the genetics of psychotic mood disorders.Semantic proximity Read ↗

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