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Article

Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder.

JAMA psychiatry - 1 Jun 2013

Kandaswamy Radhika, McQuillin Andrew, Sharp Sally I, Fiorentino Alessia, Anjorin Adebayo, Blizard Robert A, Curtis David, Gurling Hugh M D

Abstract excerpt

IMPORTANCE: Genetic markers at the gene encoding the metabotropic glutamate receptor 3 (GRM3) showed allelic association with bipolar disorder. OBJECTIVE: To screen the GRM3 gene and adjacent control regions of genomic DNA in volunteers with bipolar affective disorder for mutations increasing susceptibility to bipolar disorder. DESIGN: Sequencing and high-resolution melting curve analysis of DNA followed by...

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Source

Identifiers

PMID: 23575746
DOI: 10.1001/jamapsychiatry.2013.38

Genes

GRM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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