Article
Neurotransmission and bipolar disorder: a systematic family-based association study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Shi Jiajun, Badner Judith A, Hattori Eiji, Potash James B, Willour Virginia L, McMahon Francis J, Gershon Elliot S, Liu Chunyu
Abstract excerpt
Neurotransmission pathways/systems have been proposed to be involved in the pathophysiology and treatment of bipolar disorder for over 40 years. In order to test the hypothesis that common variants of genes in one or more of five neurotransmission systems confer risk for bipolar disorder, we analyzed 1,005 tag single nucleotide polymorphisms in 90 genes from dopaminergic, serotonergic, noradrenergic, GABAergic,...
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