Article
Serotonin transporter deficient mice are vulnerable to escape deficits following inescapable shocks.
Genes, brain, and behavior - 1 Mar 2011
Muller J M, Morelli E, Ansorge M, Gingrich J A
Abstract excerpt
Modulation of serotonin transporter (5-HTT) function causes changes in affective behavior, both in humans and rodents. Stressful life events likewise affect emotional behavior. In humans, a low-expressing genetic 5-htt variant, the s allele of the 5-htt linked promoter region, has been associated with increased risk for depression only where there was a history of stressful life events. To investigate this gene...
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