Article
Immunosuppressive cytokine gene polymorphisms and outcome after related and unrelated hematopoietic cell transplantation in a chinese population.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Apr 2011
Xiao Haowen, Cao Weijie, Lai Xiaoyu, Luo Yi, Shi Jimin, Tan Yamin, He Jingsong, Xie Wanzhuo, Meng Xiaojian, Zheng Weiyan, Zheng Gaofeng, Han Xiaoyan, Jin Lai, Zhang Lifei, Wang Yingjia, Yu Xiaohong, Cai Zhen, Lin Maofang, Ye Xiujin, Huang He
Abstract excerpt
Cytokine gene polymorphisms can affect the outcome of allogeneic hematopoietic stem cell transplantation. We analyzed 6 single nucleotide polymorphisms in 3 immunosuppressive cytokine genes, TGFβ1-509(C>T), +869(T>C), TGFβ1 receptor II (TGFβ1RII) +1167(C>T, codon389 AAC/AAT), and IL-10-1082(A>G), -819(T>C), -592(A>C), in a cohort of 138 pairs of recipients and their unrelated donors and a second cohort of 102...
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