Article
Association of cytokine gene polymorphisms with the complications of allogeneic haematopoietic stem cell transplantation.
Human immunology - 1 Nov 2017
Dukat-Mazurek Anna, Bieniaszewska Maria, Hellmann Andrzej, Moszkowska Grażyna, Trzonkowski Piotr
Abstract excerpt
The purpose of our study was to confirm the prevalence of the association between single nucleotide polymorphisms present in genes encoding cytokines and the complications occurring after haematopoietic stem cell transplantation (HSCT). 108 recipients and 81 donors were typed for TNF-α (-308), TGF-β1 (codon 10, 25), IL-10 (-1082, -819, -592), IL-6 (-174) and INF-γ (+874). Our studies have shown a tendency toward...
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