Article
Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated.
The Journal of biological chemistry - 17 Dec 2010
Mehta Monika, Braberg Hannes, Wang Shuyi, Lozsa Anita, Shales Michael, Solache Alejandra, Krogan Nevan J, Keogh Michael-Christopher
Abstract excerpt
The multi-functional histone variant Htz1 (Saccharomyces cerevisiae H2A.Z) is acetylated on up to four N-terminal lysines at positions 3, 8, 10, and 14. It has thus been posited that specific acetylated forms of the histone could regulate distinct roles. Antibodies against Htz1-K8(Ac), -K10(Ac), and -K14(Ac) show that all three modifications are added by Esa1 acetyltransferase and removed by Hda1 deacetylase....
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