Article
MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation.
Epigenetics - 1 Feb 2011
Lee Dong-Hoon, Tran Diana A, Singh Purnima, Oates Nathan, Rivas Guillermo E, Larson Garrett P, Pfeifer Gerd P, Szabó Piroska E
Abstract excerpt
5-methyl-C (5mC) and 5-hydroxymethyl-C (5hmC) are epigenetic marks with well known and putative roles in gene regulation, respectively. These two DNA covalent modifications cannot be distinguished by bisulfite sequencing or restriction digestion, the standard methods of 5mC detection. The methyla...
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