Article

DAMEfinder: A method to detect differential allele-specific methylation

2019-10-10

Abstract excerpt

DNA methylation is a highly studied epigenetic signature that is associated with regulation of gene expression, whereby genes with high levels of promoter methylation are generally repressed. Genomic imprinting occurs when one of the parental alleles is methylated, i.e, when there is inherited allele-specific methylation (ASM). A special case of imprinting occurs during X chromosome inactivation in females, where...

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Literature Corpus work: 483cf80b-c279-50c1-8a22-43fc7a3680a8
DOI: 10.1101/800383

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