Article
Association of polymorphisms in the genes of the urokinase plasminogen activation system with susceptibility to and severity of non-small cell lung cancer.
Clinica chimica acta; international journal of clinical chemistry - 14 Jan 2011
Shih Chuen-Ming, Kuo Wu-Hsien, Lin Chiao-Wen, Chen Wei, Cheng Wei-Erh, Chen Shuo-Chueh, Lee Yao-Ling
Abstract excerpt
BACKGROUND: Urokinase plasminogen activating (uPA) system is implicated in neoplastic progression. High tissue levels of uPA system components correlate with a poor prognosis in lung cancer. The present study examined the single nucleotide polymorphisms (SNPs) of uPA and the corresponding recepto...
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