Article
Genetic polymorphism of the plasminogen activator inhibitor-1 is associated with an increased risk of endometrial cancer.
Journal of surgical oncology - 1 Dec 2011
Su Chung-Kuang, Yeh Kun-Tu, Yeh Chao-Bin, Wang Po-Hui, Ho Esther Shih-Chu, Chou Ming-Chih, Liu Kai-Cheng, Yang Shun-Fa, Yi Yu-Chiao
Abstract excerpt
BACKGROUND AND OBJECTIVES: To investigate the association of uPA system genes, including uPA, uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 gene polymorphisms, with risk of endometrial cancer. METHODS: In the present case control study, we enrolled a total of 134 patients with endometrial cancer confirmed by histopathology and 302 unrelated healthy individuals. Genetic polymorphisms of uPA...
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