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Article

Identification of uPAR-positive chemoresistant cells in small cell lung cancer.

PloS one - 28 Feb 2007

Gutova Margarita, Najbauer Joseph, Gevorgyan Anna, Metz Marianne Z, Weng Yehua, Shih Chu-Chih, Aboody Karen S

Abstract excerpt

BACKGROUND: The urokinase plasminogen activator (uPA) and its receptor (uPAR/CD87) are major regulators of extracellular matrix degradation and are involved in cell migration and invasion under physiological and pathological conditions. The uPA/uPAR system has been of great interest in cancer research because it is involved in the development of most invasive cancer phenotypes and is a strong predictor of poor...

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Identifiers

PMID: 17327908
DOI: 10.1371/journal.pone.0000243
PMCID: PMC1800348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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