Article
Lack of association of the N-acetyltransferase NAT1*10 allele with prostate cancer incidence, grade, or stage among smokers in Finland.
Biochemical genetics - 1 Feb 2011
Kidd LaCreis R, Hein David W, Woodson Karen, Taylor Philip R, Albanes Demetrius, Virtamo Jarmo, Tangrea Joseph A
Abstract excerpt
Genetic variations in xenobiotic metabolizing genes can influence susceptibility to many environmentally induced cancers. Inheritance of the N-acetyltransferase 1 allele (NAT1*10), linked with increased metabolic activation of pro-carcinogens, is associated with an increased susceptibility to many cancers in which cigarette- or meat-derived carcinogens have been implicated in their etiology. The role of NAT1*10...
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