Article
Acetylation genotype and the genetic susceptibility to prostate cancer in a southern European population.
The Prostate - 1 Aug 2005
Costa Sandra, Pinto Daniela, Morais Antonio, Vasconcelos André, Oliveira Jorge, Lopes Carlos, Medeiros Rui
Abstract excerpt
BACKGROUND: Epidemiologic studies have suggested that environmental factors and diet are important risk factors in the pathogenesis of prostate cancer. The N-acetyltransferases (NAT) are important enzymes in activation and inactivation of various carcinogens, including those found in well-cooked meat and cigarette smoke. METHODS: We analyzed DNA samples from 146 prostate cancer patients and 174 healthy men. We...
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