Article
N-acetyltransferase 1 polymorphism and bladder cancer susceptibility: a meta-analysis of epidemiological studies.
The Journal of international medical research - 1 Feb 2013
Wu Ke, Wang Xianding, Xie Zhiyuan, Liu Zhihong, Lu Yiping
Abstract excerpt
OBJECTIVE: This meta-analysis was conducted to summarize the association between an N-acetyltransferase 1 (NAT1) gene polymorphism and bladder cancer risk. METHODS: PubMed® and EMBASE databases were searched to identify studies that examined the effect of the NAT1*10 allele on the risk of bladder cancer. RESULTS: Eleven case-control studies, which included 3311 bladder cancer cases and 3906 control subjects, met...
Topics
- Alleles
- Arylamine N-Acetyltransferase
- Genetic Predisposition to Disease
- Humans
- Isoenzymes
- Odds Ratio
- Polymorphism, Genetic
- Urinary Bladder Neoplasms
