Article
N-acetyltransferase 2 polymorphisms, tobacco smoking, and breast cancer risk in the breast and prostate cancer cohort consortium.
American journal of epidemiology - 1 Dec 2011
Cox David G, Dostal Lucie, Hunter David J, Le Marchand Loïc, Hoover Robert, Ziegler Regina G, Thun Michael J
Abstract excerpt
Common polymorphisms in the N-acetyltransferase 2 gene (NAT2) modify the association between cigarette smoking and bladder cancer and have been hypothesized to determine whether active cigarette smoking increases breast cancer risk. The authors sought to replicate the latter hypothesis in a prospective analysis of 6,900 breast cancer cases and 9,903 matched controls drawn from 6 cohorts (1989-2006) in the...
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