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Article

Copy number variation of FCGR3B is associated with susceptibility to idiopathic pulmonary fibrosis.

Respiration; international review of thoracic diseases - 1 Jan 2011

Bournazos Stylianos, Bournazou Irini, Murchison John T, Wallace William A, McFarlane Pauline, Hirani Nikhil, Simpson A John, Dransfield Ian, Hart Simon P

Abstract excerpt

BACKGROUND: Several genes exhibit copy number variation (CNV), including FCGR3B which encodes the IgG receptor FcγRIIIb. Engagement of Fcγ receptors by IgG complexes may contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF). OBJECTIVES: To investigate whether FCGR3B CNV is associated with susceptibility to IPF. METHODS: In a case-control study we compared FCGR3B copy number in 142 patients with...

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Identifiers

PMID: 21109729
DOI: 10.1159/000321997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Copy number variation of FCGR3B is associated with susceptibility to idiopathic pulmonary fibrosis.PMID 21109729Read ↗

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