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Article

Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production.

Archives of general psychiatry - 1 Oct 2010

Halmøy Anne, Johansson Stefan, Winge Ingeborg, McKinney Jeffrey A, Knappskog Per M, Haavik Jan

Abstract excerpt

CONTEXT: Exposure to adverse events during prenatal and postnatal development, as well as serotonin deficiency, have been implicated in disturbances of mood and impulsivity, but the underlying mechanisms are unknown. OBJECTIVE: To investigate the long-term effects of an impaired serotonin synthesis on the developing human brain, we studied the effects of nonsynonymous mutations affecting tryptophan hydroxylase...

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Source

Identifiers

PMID: 20921119
DOI: 10.1001/archgenpsychiatry.2010.124

Genes

TPH1
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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