Article
Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Sept 2012
Lesch Klaus-Peter, Araragi Naozumi, Waider Jonas, van den Hove Daniel, Gutknecht Lise
Abstract excerpt
Aggression, which comprises multi-faceted traits ranging from negative emotionality to antisocial behaviour, is influenced by an interaction of biological, psychological and social variables. Failure in social adjustment, aggressiveness and violence represent the most detrimental long-term outcome of neurodevelopmental disorders. With the exception of brain-specific tryptophan hydroxylase-2 (Tph2), which...
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