Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric Outcomes

15 Jul 2014

Abstract excerpt

The serotonin receptor 5-HT2A (encoded by HTR2A) is an important regulator of fetal brain development and adult cognitive function. Environmental signals that induce epigenetic changes of serotonin response genes, including HTR2A, have been implicated in adverse mental health outcomes. The objective of this perspective article is to address the medical implications of HTR2A epigenetic regulation, which has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent and Pediatric Healthcare
Share to Child and Adolescent Psychosocial and Emotional Development
Share to Maternal Mental Health During Pregnancy and Postpartum

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25043477
DOI: 10.1002/jcb.24883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric OutcomesPMID 25043477Read ↗

Stress exposure and psychopathology alter methylation of the serotonin receptor 2A (HTR2A) gene in preschoolers.Semantic proximity Read ↗

Epigenetic Alterations and Prenatal Maternal DepressionSemantic proximity Read ↗

Maternal Metabolic State and Fetal Sex and Genotype Modulate Methylation of the Serotonin Receptor Type 2A Gene (HTR2A) in the Human PlacentaSemantic proximity Read ↗

Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in OffspringSemantic proximity Read ↗

From Womb to Mind: Prenatal Epigenetic Influences on Mental Health DisordersSemantic proximity Read ↗

Epigenetic modifications appear in the human placenta following anxiety and depression during pregnancySemantic proximity Read ↗

Epigenetic regulation of serotonin transporter in psychiatric disorders.Semantic proximity Read ↗

Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancySemantic proximity Read ↗

Placental epigenetic signatures of maternal distress in glucocorticoid-related genes and newborn outcomes: A study of Spanish primiparous womenSemantic proximity Read ↗

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

REVIEW ARTICLE: Epigenetics in the PlacentaSemantic proximity Read ↗

Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.