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Article

Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH.

Biochemistry - 9 Nov 2010

Fledderman Emily L, Fujii Ken, Ghanam Ruba H, Waki Kayoko, Prevelige Peter E, Freed Eric O, Saad Jamil S

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) encodes a polypeptide called Gag that is capable of forming virus-like particles (VLPs) in vitro in the absence of other cellular or viral constituents. During the late phase of HIV-1 infection, Gag polyproteins are transported to the plasma membrane (PM) for assembly. A combination of in vivo, in vitro, and structural studies have shown that Gag targeting and assembly...

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Share to gag Gene Products, Human Immunodeficiency Virus
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20886905
DOI: 10.1021/bi101245j
PMCID: PMC3032006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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