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Article

Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer.

PLoS biology - 1 Sept 2020

Selzer Lisa, Su Zhaoming, Pintilie Grigore D, Chiu Wah, Kirkegaard Karla

Abstract excerpt

Matrix proteins are encoded by many enveloped viruses, including influenza viruses, herpes viruses, and coronaviruses. Underneath the viral envelope of influenza virus, matrix protein 1 (M1) forms an oligomeric layer critical for particle stability and pH-dependent RNA genome release. However, high-resolution structures of full-length monomeric M1 and the matrix layer have not been available, impeding antiviral...

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Identifiers

PMID: 32997652
DOI: 10.1371/journal.pbio.3000827
PMCID: PMC7549809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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