Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pH.

Journal of virology - 15 Jun 2016

Fraser Johanna E, Rawlinson Stephen M, Heaton Steven M, Jans David A

Abstract excerpt

UNLABELLED: The nucleolar subcompartment of the nucleus is increasingly recognized as an important target of RNA viruses. Here we document for the first time the ability of dengue virus (DENV) polymerase, nonstructural protein 5 (NS5), to accumulate within the nucleolus of infected cells and to target green fluorescent protein (GFP) to the nucleolus of live transfected cells. Intriguingly, NS5 exchange between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleolus
Share to Chlorocebus aethiops
Share to Dengue Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Space

Share to Green Fluorescent Proteins

Share to Hydrogen-Ion Concentration

Share to Vero Cells

Share to Viral Nonstructural Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 27076639
DOI: 10.1128/JVI.02727-15
PMCID: PMC4886796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pH.PMID 27076639Read ↗

Conformational Changes in the Adenovirus Hexon Subunit Responsible for Regulating Cytoplasmic Dynein RecruitmentSemantic proximity Read ↗

Acidic pH of early endosomes governs SARS-CoV-2 transport in host cellsSemantic proximity Read ↗

Nucleocytoplasmic shuttling of the West Nile virus RNA ‐dependent RNA polymerase NS5 is critical to infectionSemantic proximity Read ↗

Involvement of the nucleolus in replication of human virusesSemantic proximity Read ↗

Enterovirus D68 capsid formation and stability requires acidic compartmentsSemantic proximity Read ↗

Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular LocalizationSemantic proximity Read ↗

Rab 5 Is Required for the Cellular Entry of Dengue and West Nile VirusesSemantic proximity Read ↗

In Vitro and In Vivo Stability of P884T, a Mutation that Relocalizes Dengue Virus 2 Non-structural Protein 5.Semantic proximity Read ↗

Equine Rhinitis A Virus Mutants with Altered Acid Resistance Unveil a Key Role of VP3 and Intrasubunit Interactions in the Control of the pH Stability of the Aphthovirus Capsid.Semantic proximity Read ↗

Nucleolar localization of non-structural protein 3b, a protein specifically encoded by the severe acute respiratory syndrome coronavirusSemantic proximity Read ↗

Dengue virus NS1 undergoes partial nuclear translocation to modulate host transcription and support viral replicationSemantic proximity Read ↗

Delineation and Modelling of a Nucleolar Retention Signal in the Coronavirus Nucleocapsid ProteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.