Article
Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease.
Neuron - 2 May 2018
Nanou Evanthia, Catterall William A
Abstract excerpt
Voltage-gated calcium channels couple depolarization of the cell-surface membrane to entry of calcium, which triggers secretion, contraction, neurotransmission, gene expression, and other physiological responses. They are encoded by ten genes, which generate three voltage-gated calcium channel subfamilies: CaV1; CaV2; and CaV3. At synapses, CaV2 channels form large signaling complexes in the presynaptic nerve...
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