Article
Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders.
Progress in neurobiology - 1 Nov 2015
Heyes Samuel, Pratt Wendy S, Rees Elliott, Dahimene Shehrazade, Ferron Laurent, Owen Michael J, Dolphin Annette C
Abstract excerpt
This review summarises genetic studies in which calcium channel genes have been connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and schizophrenia to autism spectrum disorders and intellectual impairment. Among many other genes, striking numbers of the calcium channel gene superfamily have been implicated in the aetiology of these diseases by various DNA analysis techniques. We will...
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