Article
The Density of CD10 Corresponds to Commitment and Progression in the Human B Lymphoid Lineage
23 Sept 2010
Abstract excerpt
BACKGROUND: Requirements for human B lymphopoiesis are still poorly understood, and that has hampered investigation of differentiation events. For example, there are few cell surface antigens that can be used as milestones of lineage progression. The CD10 ectoenzyme is one such marker and has been used to define CLP, but we found substantial tissue specific variations in CD10 levels, and there was no information...
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