Article
Initial CD34+ cell-enrichment of cord blood determines hematopoietic stem/progenitor cell yield upon ex vivo expansion.
Journal of cellular biochemistry - 1 Jul 2011
Andrade Pedro Z, da Silva Cláudia Lobato, dos Santos Francisco, Almeida-Porada Graça, Cabral Joaquim M S
Abstract excerpt
Since umbilical cord blood (UCB), contains a limited hematopoietic stem/progenitor cells (HSC) number, successful expansion protocols are needed to overcome the hurdles associated with inadequate numbers of HSC collected for transplantation. UCB cultures were performed using a human stromal-based serum-free culture system to evaluate the effect of different initial CD34(+) cell enrichments (Low: 24 ± 1.8%,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
