Article
Characterization of a hierarchy in human acute myeloid leukemia progenitor cells
1 Jun 1996
Abstract excerpt
Despite the usual uniform and primitive appearance of cells derived from the leukemic clone in most patients with acute myeloid leukemia (AML), there is considerable heterogeneity among leukemic blasts, particularly with respect to their capacity to proliferate and/or self renew. We have assessed whether these differences in proliferative potential are correlated with the phenotypic changes that characterize...
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