Article
Phenotypic and functional characterization of mobilized peripheral blood CD34+ cells coexpressing different levels of c-Kit.
Leukemia research - 1 Apr 1998
Kuçi S, Taylor G, Neu S, Schumm M, Niethammer D, Handgretinger R
Abstract excerpt
In this report we evaluated the exact expression pattern of c-Kit on mobilized peripheral blood (PB) CD34+ cells. Using a monoclonal antibody against CD117 antigen (95C3), flow cytometric analysis revealed that approximately 25% of the mobilized PB CD34+ cells coexpress c-Kit. This cell fraction...
Topics
- Antigens, CD34
- Antigens, CD7
- CD2 Antigens
- Cell Separation
- Colony-Forming Units Assay
- Flow Cytometry
- Hematopoietic Stem Cell Mobilization
- Humans
- Leukocytes, Mononuclear
- Phenotype
- Proto-Oncogene Proteins c-kit
- Reactive Oxygen Species
- Time Factors