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Article

Crohn's Disease Localization Displays Different Predisposing Genetic Variants.

PloS one - 1 Jan 2017

Palmieri Orazio, Bossa Fabrizio, Valvano Maria Rosa, Corritore Giuseppe, Latiano Tiziana, Martino Giuseppina, D'Incà Renata, Cucchiara Salvatore, Pastore Maria, D'Altilia Mario, Scimeca Daniela, Biscaglia Giuseppe, Andriulli Angelo, Latiano Anna

Abstract excerpt

BACKGROUND: Crohn's disease (CD) is a pathologic condition with different clinical expressions that may reflect an interplay between genetics and environmental factors. Recently, it has been highlighted that three genetic markers, NOD2, MHC and MST1, were associated to distinct CD sites, supporting the concept that genetic variations may contribute to localize CD. Genetic markers, previously shown to be...

Topics

Adolescent
Adult
Crohn Disease
Female
Genetic Markers
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Ileum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Single Nucleotide

ROC Curve

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28052082
DOI: 10.1371/journal.pone.0168821
PMCID: PMC5215692

Genes

MST1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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