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Article

Gene-based testing of interactions in association studies of quantitative traits.

PLoS genetics - 1 Jan 2013

Ma Li, Clark Andrew G, Keinan Alon

Abstract excerpt

Various methods have been developed for identifying gene-gene interactions in genome-wide association studies (GWAS). However, most methods focus on individual markers as the testing unit, and the large number of such tests drastically erodes statistical power. In this study, we propose novel int...

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Share to Computer Simulation
Share to Epistasis, Genetic
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Models, Theoretical

Share to Polymorphism, Single Nucleotide

Share to Protein Binding

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 23468652
DOI: 10.1371/journal.pgen.1003321
PMCID: PMC3585009

Genes

NEDD9
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23468652-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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