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Article

INTERSNP: genome-wide interaction analysis guided by a priori information.

Bioinformatics (Oxford, England) - 15 Dec 2009

Herold Christine, Steffens Michael, Brockschmidt Felix F, Baur Max P, Becker Tim

Abstract excerpt

SUMMARY: Genome-wide association studies (GWAS) have lead to the identification of hundreds of genomic regions associated with complex diseases. Nevertheless, a large fraction of their heritability remains unexplained. Interaction between genetic variants is one of several putative explanations for the 'case of missing heritability' and, therefore, a compelling next analysis step. However, genome-wide interaction...

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PMID: 19837719
DOI: 10.1093/bioinformatics/btp596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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