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Article

Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis.

BMC genetics - 6 Feb 2015

Grange Laura, Bureau Jean-François, Nikolayeva Iryna, Paul Richard, Van Steen Kristel, Schwikowski Benno, Sakuntabhai Anavaj

Abstract excerpt

BACKGROUND: Deciphering the genetic architecture of complex traits is still a major challenge for human genetics. In most cases, genome-wide association studies have only partially explained the heritability of traits and diseases. Epistasis, one potentially important cause of this missing herita...

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Share to Chromosomes, Human, Pair 6
Share to Epistasis, Genetic
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 25655172
DOI: 10.1186/s12863-015-0174-3
PMCID: PMC4341885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25655172-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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