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Article

Genome-wide gene-gene interaction analysis for next-generation sequencing.

European journal of human genetics : EJHG - 1 Mar 2016

Zhao Jinying, Zhu Yun, Xiong Momiao

Abstract excerpt

The critical barrier in interaction analysis for next-generation sequencing (NGS) data is that the traditional pairwise interaction analysis that is suitable for common variants is difficult to apply to rare variants because of their prohibitive computational time, large number of tests and low power. The great challenges for successful detection of interactions with NGS data are (1) the demands in the paradigm...

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Identifiers

PMID: 26173972
DOI: 10.1038/ejhg.2015.147
PMCID: PMC4755380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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