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Article

Protein kinase C{delta} deficiency accelerates neointimal lesions of mouse injured artery involving delayed reendothelialization and vasohibin-1 accumulation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2010

Bai Xue, Margariti Andriana, Hu Yanhua, Sato Yasufumi, Zeng Lingfang, Ivetic Aleksandar, Habi Ouassila, Mason Justin C, Wang Xian, Xu Qingbo

Abstract excerpt

OBJECTIVE: To use protein kinase C (PKC) δ-knockout mice to investigate the role of PKCδ in lesion development and to understand the underlying mechanism of the vascular disease. METHODS AND RESULTS: PKCδ functions as a signal transducer mediating several essential functions of cell proliferation and apoptosis. However, the effect of PKCδ on neointimal formation in wire-injured vessels is unknown. Three weeks...

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Source

Identifiers

PMID: 20884873
DOI: 10.1161/ATVBAHA.110.215723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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