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Article

Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2004

Sakata Yasuhiko, Xiang Fan, Chen Zhiping, Kiriyama Yoriko, Kamei Caramai N, Simon Daniel I, Chin Michael T

Abstract excerpt

OBJECTIVE: To determine the role of the cardiovascular-restricted, hairy-related bHLH transcription factor, CHF1/Hey2, in the biological response to vascular injury. METHODS AND RESULTS: We investigated the response of CHF1/Hey2-deficient mice to vascular injury in vivo and the response of primary cultured vascular smooth muscle cells (VSMCs) from these mice to growth factors in vitro. Neointima formation after...

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Source

Identifiers

PMID: 15345511
DOI: 10.1161/01.ATV.0000143936.77094.a4

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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