Article
The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2016
Stiber Jonathan A, Wu Jiao-Hui, Zhang Lisheng, Nepliouev Igor, Zhang Zhu-Shan, Bryson Victoria G, Brian Leigh, Bentley Rex C, Gordon-Weeks Phillip R, Rosenberg Paul B, Freedman Neil J
Abstract excerpt
OBJECTIVE: Vascular smooth muscle cell (SMC) migration is regulated by cytoskeletal remodeling as well as by certain transient receptor potential (TRP) channels, nonselective cation channels that modulate calcium influx. Proper function of multiple subfamily C TRP (TRPC) channels requires the scaffolding protein Homer 1, which associates with the actin-binding protein Drebrin. We found that SMC Drebrin expression...
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