Article
Binding and cleavage of CRISPR RNA by Cas6.
RNA (New York, N.Y.) - 1 Nov 2010
Carte Jason, Pfister Neil T, Compton Mark M, Terns Rebecca M, Terns Michael P
Abstract excerpt
The CRISPR-Cas system provides many prokaryotes with acquired resistance to viruses and other mobile genetic elements. The core components of this defense system are small, host-encoded prokaryotic silencing (psi)RNAs and Cas (CRISPR-associated) proteins. Invader-derived sequences within the psiRNAs guide Cas effector proteins to recognize and silence invader nucleic acids. Critical for CRISPR-Cas defense is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
