Article
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
The Journal of biological chemistry - 18 Jul 2008
Beloglazova Natalia, Brown Greg, Zimmerman Matthew D, Proudfoot Michael, Makarova Kira S, Kudritska Marina, Kochinyan Samvel, Wang Shuren, Chruszcz Maksymilian, Minor Wladek, Koonin Eugene V, Edwards Aled M, Savchenko Alexei, Yakunin Alexander F
Abstract excerpt
Clustered regularly interspaced short palindromic repeats (CRISPRs) together with the associated CAS proteins protect microbial cells from invasion by foreign genetic elements using presently unknown molecular mechanisms. All CRISPR systems contain proteins of the CAS2 family, suggesting that the...
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