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Article

BRCA1 promoter methylation in peripheral blood cells is associated with increased risk of breast cancer with BRCA1 promoter methylation.

Breast cancer research and treatment - 1 Aug 2011

Iwamoto Takashi, Yamamoto Noriaki, Taguchi Tetsuya, Tamaki Yasuhiro, Noguchi Shinzaburo

Abstract excerpt

BRCA1 promoter methylation reportedly plays an important part in the pathogenesis of human breast cancer. In the present study, we investigated whether or not BRCA1 promoter methylation in peripheral blood cells (PBCs) can serve as a risk factor for developing breast cancer. The association of BRCA1 promoter methylation in PBCs with breast cancer risk was examined in a case-control study (200 breast cancer...

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Source

Identifiers

PMID: 20882403
DOI: 10.1007/s10549-010-1188-1

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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