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Article

Peripheral blood BRCA1 methylation profiling to predict familial ovarian cancer.

Journal of gynecologic oncology - 1 Mar 2021

Jung Yuyeon, Hur Sooyoung, Liu JingJing, Lee Sanha, Kang Byung Soo, Kim Myungshin, Choi Youn Jin

Abstract excerpt

OBJECTIVE: Familial cancer appears at a young age and its incidence is increasing. About 12% of familial ovarian cancer cases are associated with BRCA1/2 mutations (BRCAm). In this study, we investigated BRCA1 methylation may predict ovarian cancer in those with a family history of cancer (FHC) but without BRCA1/2 mutations (BRCAwt). METHODS: Using peripheral blood DNA from 55 subjects without a history of cancer...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33470065
DOI: 10.3802/jgo.2021.32.e23
PMCID: PMC7930454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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