Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation of BRCA1 promoter region is associated with unfavorable prognosis in women with early-stage breast cancer.

PloS one - 1 Jan 2013

Hsu Nicholas C, Huang Ya-Fang, Yokoyama Kazunari K, Chu Pei-Yi, Chen Fang-Ming, Hou Ming-Feng

Abstract excerpt

BRCA1-associated breast cancers are associated with particular features such as early onset, poor histological differentiation, and hormone receptor negativity. Previous studies conducted in Taiwanese population showed that the mutation of BRCA1 gene does not play a significant role in the occurrence of breast cancer. The present study explored methylation of BRCA1 promoter and its relationship to clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to Carcinoma, Ductal, Breast

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Immunoenzyme Techniques

Share to Lymphatic Metastasis

Share to Neoplasm Grading

Share to Neoplasm Staging

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 23405268
DOI: 10.1371/journal.pone.0056256
PMCID: PMC3566056

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation of BRCA1 promoter region is associated with unfavorable prognosis in women with early-stage breast cancer.PMID 23405268Read ↗

Association of BRCA1 Promoter Methylation with Breast Cancer in Asia: A Meta- AnalysisSemantic proximity Read ↗

Aberrant promoter methylation of the CHD1 gene may contribute to the pathogenesis of breast cancer: a meta-analysis.Semantic proximity Read ↗

BRCA1 deficiency is a recurrent event in early-onset triple-negative breast cancer: a comprehensive analysis of germline mutations and somatic promoter methylationSemantic proximity Read ↗

Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women.Semantic proximity Read ↗

Prognostic value of BRCA1 promoter methylation for patients with epithelial ovarian cancer.Semantic proximity Read ↗

BRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC.Semantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood is associated with the risk of triple‐negative breast cancerSemantic proximity Read ↗

BRCA1 promoter methylation predicts adverse ovarian cancer prognosisSemantic proximity Read ↗

Clinicopathological features, genetic alterations, and BRCA1 promoter methylation in Japanese male patients with breast cancer.Semantic proximity Read ↗

Methylation Profile of BRCA1, RASSF1A and ER in Vietnamese Women with Ovarian CancerSemantic proximity Read ↗

BRCA1 disease-associated haplotypes in Singapore Malay women with early-onset breast/ovarian cancer.Semantic proximity Read ↗

Epigenetic changes in BRCA1-mutated familial breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.