Article
Models of population-based analyses for data collected from large extended families.
European journal of epidemiology - 1 Dec 2010
Wang Wenyu, Lee Elisa T, Howard Barbara V, Fabsitz Richard R, Devereux Richard B, MacCluer Jean W, Laston Sandra, Comuzzie Anthony G, Shara Nawar M, Welty Thomas K
Abstract excerpt
Large studies of extended families usually collect valuable phenotypic data that may have scientific value for purposes other than testing genetic hypotheses if the families were not selected in a biased manner. These purposes include assessing population-based associations of diseases with risk factors/covariates and estimating population characteristics such as disease prevalence and incidence. Relatedness...
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