Article
Bivariate traits association analysis using generalized estimating equations in family data.
Statistical applications in genetics and molecular biology - 5 May 2020
de Andrade Mariza, Mazo Lopera Mauricio A, Duarte Nubia E
Abstract excerpt
Genome wide association study (GWAS) is becoming fundamental in the arduous task of deciphering the etiology of complex diseases. The majority of the statistical models used to address the genes-disease association consider a single response variable. However, it is common for certain diseases to have correlated phenotypes such as in cardiovascular diseases. Usually, GWAS typically sample unrelated individuals...
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