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Article

Power calculations for familial aggregation studies.

Genetic epidemiology - 1 May 2004

Rabbee Nusrat, Betensky Rebecca A

Abstract excerpt

Family studies are frequently undertaken as the first step in the search for genetic determinants of disease. Significant familial aggregation of disease is suggestive of a genetic etiology for the disease, and may lead to more focused genetic analyses. Many methods have been proposed in the literature for the analysis of family studies. One model that is appealing for its simplicity of computation and the...

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PMID: 15095391
DOI: 10.1002/gepi.10312

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